Welcome to the other side of the tracks, fflowers. You're going to have a great time downtown, and you'll find the gambling and the comps to be a lot better than up on the Strip. We only stay downtown (only exception in the past few years was a couple of nights at Sam's Town), usually at MSS and the Plaza, sometimes Four Queens. Lots of good VP, I especially like MSS and the Cal (the scratch-off tickets for quads or better at MSS adds some EV) and at Four Queens (generous CB, progressive 10/7 DB, plenty of 9/6 JoB, nice marketing offers). You can't do better than the El Cortez for blackjack. We kind of like the double deck game there, the problem with single deck is that the tables are usually crowded and you'll only get two hands per deck.
Plenty of good promos all over downtown; probably the El Cortez and the Plaza are the best for various promos.
Lots of good food downtown. The clientele at the Cal is about 80% Hawaiian, Boyd runs air packages from Honolulu, so there's good mom-and-pop Hawaiian food at Aloha Specialties, and fantastic ice cream at Lappert's, a chain out of Hawaii. The Plaza has a really good Hawaiian place now, Island Sushi (hell of a good poke bar). At the Golden Gate, DuPar's is pretty good for diner food; at Four Queens, there's Magnolia's for cheap prime rib and coffee shop food (plenty of BOGOs out there). I really like the food at the El Cortez; Roberta's (yeah, it's The Flame now) is terrific, good walleye pike, good steaks, great king crab. Across the street, the Kebab Korner has been mentioned, and is very good, so is the little dumpy pizza place next to it (Uncle Joe's, I think). The Thai place across the street is new, haven't been there. Skip Mamita's, they have forgettable Mexican and Cuban food. Another good place for Thai and Chinese food, though, is Thai Vegas, off Fremont on 4th Street.
Then, you have some cool places a short bus ride away, like the coffee shop at Jerry's Nugget, in North Las Vegas, or Dona Maria's Tamales (good Mexican food) down off of Charleston.
Guess you can tell that I'm a bit food-focused.
Anyway, glad you're going to make it downtown, have a wonderful time, can't wait to hear how you do!