My head picks the Chiefs, due to the mental boost from recent Mahomes/ Reid / team success in the playoffs. Experience in the playoffs might add an unknown edge for them. Plus, the Chiefs are 6-1 against the spread recently. OTOH, the 49ers are 2+ point favorites and may have the better overall team / roster, man for man. Gotta admire McCaffery's varied on-field contributions plus off-field charity work. My heart choice is with the 49ers. It'd be enjoyable to see how the respective defenses handle the opposing running games..might be a key if KC can limit Bosa's ferocity. The O/U? 47.5 ? Might take the over..but who the hell knows.