Researchers from the University of Pittsburgh School of Medicine claim to have isolated the smallest biological molecule to date that completely and specifically neutralizes the /SARS-CoV-2/ coronavirus.
The identified antibody component, which is 10 times smaller than a full-sized antibody, has been used to construct a drug known as Ab8 for potential use as a therapeutic and prophylactic against SARS-CoV-2.
The study team reports that Ab8 is highly effective in preventing and treating SARS-CoV-2 infection in mice and hamsters. Its tiny size not only increases its potential for diffusion in tissues to better neutralize the SARS-CoV-2 coronavirus, but also makes it possible to administer the drug by alternative routes, including inhalation.
Most importantly, it does not bind to human cells ie a good sign that it won’t have negative side-effects in individuals.
Ab8 not only has potential as therapy for COVID-19, but it also could be used to keep individuals from getting SARS-CoV-2 infections, acting as a kind of prophylaxis.
Source: https://www.12news.com/article/news/health/coronavirus/researchers-hopeful-promising-covid-19-therapeutic/507-e83c6c89-568e-423d-bbe2-e52eb4e7f55a
