Thoughts?

Thoughts? Here's a thought...How many #1 Seeds make it to the Final Four...one? Maybe two? That means then that two or three each year don't make it to the Final Four. Seems to me that starting in the 2nd and going up until the Final Four, that it would make sense to bet on the ML Dog against the #1 Seed. When the #1 Seed gets upset on the way to the Final Four, the payoff can be pretty big...witness No. Iowa at +700 against Kansas, etc. Anyone have any thoughts on this? Thanks!
I don't have the numbers in front of me, but if two #1s make the final four on average, then every bet on those two teams loses, plus all the other ones that lose until the #1 is knocked off. The only reason Northern Iowa's money line was so high was becuse they were a 9 seed. Typically, the non-one-seeded final four teams are 2 or 3 seeds, and for them to beat the No. 1 see, the money line will be much lower. However, it's one component that can be used when handicapping a game, and if everything else points to an upset as well, give it a shot.