If you could anticipate all line moves, you'd be a billionaire.
If you beat the closing line consistently you'll make money.
Basically you are asking how do you handicap which is the right side.
One method is good handicapping. Some can do it, others can't.
Other things to look for:
The direction Pinnacle is leaning
Numbers that matter - for instance if you like a team -6.5 and have no idea which way it moves, play it because -7 is a lot worse and -6 is only a bit better. On the other hand if you like a team +6.5, wait cause +7 is a lot better and +6 is not a huge deal.
Public teams - teams such as the yankees, red sox, notre dame, Cowboys, Giants, USC, etc will oftne get hit by the public at game time
Public games - big games tend to see the favorite and over hit near game time