Please feel free to pm with any specific questions as Ak-Chin is my local Harrahs property. I'm guessing the difference between Tower 1 and Tower 2 is the view as there is only 1 tower. I prefer tower rooms that face west or the direction of the pool. If you're on the lower floors with a room facing west, your view will be the resort rooms. Resort rooms are the original hotel.
Hotel tower is fairly new and will be 2 years old in July. Resort rooms are the original rooms and were remodeled before they built the hotel tower. Resort rooms are larger. All have either a balcony or small patio, refrigerator, safe, in room individual coffee and the bathroom has a separate tower and tub. The carpet might be a tad dated in some rooms, otherwise rooms are nice. In some of the resort rooms, they recently redid the wall tile in the bathrooms. Tower rooms are closer to the casino and have a loft like feel. They are smaller, nicely appointed but not a lot of space for 2 people. All have in room individual coffee, refrigerator and safe. Bathroom has a large walk in shower with large showerhead and no bathtub. If there were 2 or more of us staying in the room and we were staying for more than 1 quick night, I'd request a Resort room when I made my reservation.
Sometimes I go for a quick night arriving around 8 pm and leave the next morning. Those nights I basically need a place to crash and am happy and prefer a resort room. Sometimes I arrive earlier in the day, want to enjoy the pool and/or hotel part of the property or maybe stay 2 nights. Those trips, I request a resort room on the 2nd floor. Most people want a room facing the pool. I like the rooms facing the field and enjoy looking at very little over the horizon. I also like being able to open the arcadia door and enjoy the fresh air.
I'm guessing this is your first visit to Ak-Chin and you'll probably be driving from Phoenix's airport. Ak-Chin is located about 17 miles from I 10 on Highway 347. You drive through the desert or middle of nowhere to get there.