Although I'm not that old, I can't even tell you how many times I've been to Vegas. I've been going there at least once per year every year since I turned 21.
Every trip, our goal is to try something new.
This year, we stayed the first night at the D (as is tradition. Not new, we just love that place), then we knocked the Cosmo off the bucket list. We had (3) One Bedroom Fountain View Veranda rooms, and they were, without question, the best rooms I've ever had in Las Vegas. Previously, my favorite rooms were the Spa Suites at the Palms.
Anyway, Rose.Rabbie.Lie, Wicked Spoon and Opium were AMAZING, and I recommend that you try them all. We've only been back a week, and I'm already wanting to start planning the next trip.
I could go on for days, but I enjoy brevity. If you haven't spent a good amount of time at the Cosmo, do it.