I opt for "FRUGAL", so it's downtown for me.
I've stayed at 5 different properties, and my primary criteria is cost. During '09, I was getting weekday rooms (No Fri-Sat nights) at Binion's for a whopping $19.61 per total. I'd get a comped room for those more "expensive" weekends, usually at the 4Queens or Plaza.
I could, and did get more frugal prices from Golden Gate, Vegas Club, and MSS through some online deals, but as a poker player I preferred Binion's for their $2.00/hour comps. Unfortunately, they're "closed" now.
Also took advantage of MRB "coupon", and other "deals" a diligent search by someone as frugal as I am should spend time on. My average 8+ day trips, including hotel, R/T NS airfare from Fort Lauderdale, expenses for luggage, airport shuttles, etc, and allowing $20.00/day for meals averaged was always less than $55.00 per day, and in the $40's for a few of my trips. (2009)
Not finding those types of deals anymore.
But than, unless the MRB has a bunch of great match play coupons, there is no reason for me to go to Vegas. The coupon EV paid for my trips.
Yeah, I'm a casino whore.