25 Cents for Video Poker

Am I better off playing 5 coins at a 5 cent Video Poker machine or one coin at a Quarter Video Poker Machine.?

There are many variables that can play into this decision, but in most cases the two choices will be pretty close in terms of expected value. Pick the one that you enjoy the most, but stay with these two options -- playing 2, 3, or 4 coins is almost always inferior.

If you hit a Royal Flush playing a single quarter, you get $62.50 Hit it playing five nickels and its around $200( most 5cent machines I know are progressives). Other than that, your payout will be the same if the pay table is. 9/6 Quarters and 9/6 nickels will pay the same. Most nickel machines offer lousy pay tables. If it's 8-5 or worse, you literally are throwing away your money.